FAM43B

Across TCGA patient cohorts, FAM43B mutation is significantly associated with the RNA expression of many other genes, with 1,236 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM43B-associated genes across cancer lineages are TRAV36DV7, IGKV3D-7, and DYNLT3P2. Each is linked with FAM43B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM43B-to-partner and partner-to-FAM43B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAV36DV7 grouped by FAM43B-low versus FAM43B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43B→partner) and Y-score (partner→FAM43B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAV36DV7 →	+0.442	+2.768	.003	.005	3	2
UCEC	IGKV3D-7 →	+0.453	+2.266	.001	.007	3	2
UCEC	DYNLT3P2 →	+0.403	+3.793	<.001	<.001	3	2
COAD	RNA5SP319 →	+0.377	+3.271	.006	.009	3	2
COAD	RN7SL308P →	+0.383	+3.428	.003	.007	3	2
LUAD	TP53TG3 →	+0.041	+5.481	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,236 associations by consensus.

TRAV36DV7 by FAM43B expression — UCEC

Explore this box plot interactively →