Across TCGA patient cohorts, FAM43B mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM43B-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and Ku80. Each is linked with FAM43B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM43B-to-partner and partner-to-FAM43B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43B→partner) and Y-score (partner→FAM43B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.666	+2.827	.032	.035	3	2
UCEC	ERK2 →	+0.348	+3.321	<.001	.010	3	1
UCEC	Ku80 →	+0.348	+3.013	.004	.018	3	1
UCEC	N-Ras →	-0.203	-3.308	.001	.010	3	1
UCEC	PKC-a →	+0.499	+2.820	.018	.035	3	1
UCEC	Annexin-1 →	+0.787	+2.827	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

FAM43B survival (RNA) · tumor vs normal (RNA) · all FAM43B data types