FAM43B

Across TCGA cell cohorts, FAM43B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,620 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM43B-associated GO terms across cancer lineages are Regulation of blood-brain barrier permeability, Interleukin-3-mediated signaling pathway, and Locomotory exploration behavior. Each is linked with FAM43B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM43B-to-partner and partner-to-FAM43B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of blood-brain barrier permeability grouped by FAM43B-low versus FAM43B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43B→partner) and Y-score (partner→FAM43B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of blood-brain barrier permeability →	-0.270	-0.290	<.001	.002	3	6
LUNG_NSCLC_LUAD	Interleukin-3-mediated signaling pathway →	-0.801	-0.590	<.001	<.001	3	6
SOFT_TISSUE	Locomotory exploration behavior →	+0.105	+0.904	.001	<.001	3	6
LUNG_NSCLC_LUAD	Acetylcholine biosynthetic process →	-0.719	-0.478	.004	.001	3	6
OVARY	Receptor clustering →	-0.100	-0.248	<.001	.004	3	6
BONE	rRNA metabolic process →	+0.116	+1.662	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,620 associations by consensus.

Regulation of blood-brain barrier permeability by FAM43B expression — OVARY

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