FAM43B

Across TCGA cell cohorts, FAM43B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM43B-associated genes across cancer lineages are KRTAP4-1, OR4A47, and OR2L8. Each is linked with FAM43B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM43B-to-partner and partner-to-FAM43B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-1 grouped by FAM43B-low versus FAM43B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43B→partner) and Y-score (partner→FAM43B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP4-1 →	+0.179	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4A47 →	+0.018	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR2L8 →	+0.020	+6.266	<.001	<.001	3	1
LARGE_INTESTINE	BPIFA1 →	+0.152	+2.688	<.001	.008	3	1
LARGE_INTESTINE	C16orf96 →	+0.454	+3.743	.006	.001	3	1
LARGE_INTESTINE	FBXW10 →	+0.207	+3.491	.003	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

KRTAP4-1 by FAM43B expression — BLOOD_Lymphoma

Explore this box plot interactively →