Across TCGA patient cohorts, FAM3D protein abundance is significantly associated with the RNA expression of many other genes, with 5,350 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM3D-associated genes across cancer lineages are TFF1, SMIM31, and BCAS1. Each is linked with FAM3D in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM3D-to-partner and partner-to-FAM3D results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3D→partner) and Y-score (partner→FAM3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFF1 →	+2.996	+0.936	<.001	.008	3	5
UCEC	SMIM31 →	+1.619	+1.643	.001	<.001	3	5
PDAC	BCAS1 →	+1.262	+1.050	<.001	<.001	3	5
UCEC	AGR2 →	+2.557	+1.384	.004	.001	3	4
BRCA	CREB3L1 →	+2.054	+1.096	<.001	.005	3	4
HNSC	ZG16B →	+3.314	+0.967	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,350 associations by consensus.

Exploration

FAM3D survival (RNA) · tumor vs normal (RNA) · all FAM3D data types