Across TCGA cell cohorts, FAM3D RNA expression is significantly associated with the go_rna of many other GO terms, with 1,680 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM3D-associated GO terms across cancer lineages are Positive regulation of vitamin D receptor signaling pathway, Establishment or maintenance of transmembrane electrochemical gradient, and Positive regulation of protein localization to cell periphery. Each is linked with FAM3D in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM3D-to-partner and partner-to-FAM3D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3D→partner) and Y-score (partner→FAM3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of vitamin D receptor signaling pathway →	+0.209	+2.607	<.001	.004	3	6
LARGE_INTESTINE	Establishment or maintenance of transmembrane electrochemical gradient →	+0.181	+2.571	<.001	<.001	3	6
LARGE_INTESTINE	Positive regulation of protein localization to cell periphery →	+0.096	+2.988	<.001	<.001	3	6
LIVER	Viral budding via host ESCRT complex →	+0.104	+0.079	<.001	.001	3	6
OESOPHAGUS	Postsynaptic density protein 95 clustering →	-1.298	-1.094	<.001	.006	3	5
URINARY_TRACT	Peptidyl-lysine oxidation →	-1.088	-0.454	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,680 associations by consensus.

Exploration

FAM3D survival (RNA) · tumor vs normal (RNA) · all FAM3D data types