FAM3D-AS1

Across TCGA pan-cancer cohorts, FAM3D-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FAM3D-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM3D-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM3D-AS1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PAAD show a favorable association.

UCEC, ESCA, and UVM are the cancer types where FAM3D-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.570	0.711	<.001	58	view →
ESCA	DFS	Median	All	0.214	0.922	<.001	36	view →
UVM	DFS	Tertile	III,IV	0.107	0.677	.004	27	view →
SARC	DFS	Tertile	All	0.416	0.581	.005	25	view →
ACC	OS	Quartile	All	0.598	0.952	.002	24	view →
KIRP	DFS	Median	All	0.863	0.966	.001	21	view →
COAD	OS	Median	IV	0.669	0.346	.015	17	view →
PAAD	OS	Tertile	II,III,IV	0.526	0.265	.007	12	view →
CESC	OS	Tertile	All	0.645	0.486	.023	12	view →
KIRC	OS	Median	All	0.692	0.566	.006	10	view →
CHOL	OS	Median	IV	1.000	0.286	.024	10	view →
THYM	DFS	Median	All	0.930	0.688	.033	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FAM3D-AS1–UCEC (DFS)

Open the UCEC breakdown →