Across TCGA patient cohorts, FAM3C protein abundance is significantly associated with the RNA expression of many other genes, with 9,806 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM3C-associated genes across cancer lineages are FAM3C2P, ARFGAP3, and GOLPH3. Each is linked with FAM3C in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM3C-to-partner and partner-to-FAM3C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3C→partner) and Y-score (partner→FAM3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM3C2P →	+1.233	+0.690	<.001	<.001	3	8
UCEC	ARFGAP3 →	+0.620	+0.560	.006	<.001	2	6
LSCC	GOLPH3 →	+0.476	+0.350	<.001	.002	3	4
LSCC	RHOC →	+0.623	+0.446	<.001	<.001	3	4
OV	GKAP1 →	-0.643	-0.419	.003	.002	3	4
COAD	MFSD6L →	-0.954	-0.286	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,806 associations by consensus.

Exploration

FAM3C survival (RNA) · tumor vs normal (RNA) · all FAM3C data types