Across TCGA patient cohorts, FAM3B mutation is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM3B-associated genes across cancer lineages are DPPA2P2, EEF1E1-BLOC1S5, and GOLGA6L16P. Each is linked with FAM3B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM3B-to-partner and partner-to-FAM3B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3B→partner) and Y-score (partner→FAM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	DPPA2P2 →	+0.078	+4.591	<.001	.004	3	2
UCEC	EEF1E1-BLOC1S5 →	+0.050	+4.132	<.001	.009	3	2
HNSC	GOLGA6L16P →	+0.100	+5.736	<.001	.003	3	1
HNSC	RNU4-79P →	+0.280	+7.623	<.001	<.001	3	1
HNSC	GOLGA6L11P →	+0.149	+5.303	<.001	.006	3	1
SKCM	USH2A-AS1 →	+0.090	+2.493	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

Exploration

FAM3B survival (RNA) · tumor vs normal (RNA) · all FAM3B data types