Across TCGA cell cohorts, FAM3B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,165 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FAM3B-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Serotonin secretion, and Serotonin production involved in inflammatory response. Each is linked with FAM3B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM3B-to-partner and partner-to-FAM3B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3B→partner) and Y-score (partner→FAM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of mRNA metabolic process →	+0.057	+1.173	.002	.009	3	7
LUNG_SCLC	Serotonin secretion →	+1.394	+3.519	<.001	<.001	3	6
LUNG_SCLC	Serotonin production involved in inflammatory response →	+1.394	+3.519	<.001	<.001	3	6
LUNG_SCLC	Serotonin secretion involved in inflammatory response →	+1.394	+3.519	<.001	<.001	3	6
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.053	-0.906	<.001	.002	3	5
BONE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.115	+0.086	.001	.004	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,165 associations by consensus.

Exploration

FAM3B survival (RNA) · tumor vs normal (RNA) · all FAM3B data types