FAM3A

Across TCGA patient cohorts, FAM3A protein abundance is significantly associated with the RNA expression of many other genes, with 3,624 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM3A-associated genes across cancer lineages are ZNF445, MAX, and ATM. Each is linked with FAM3A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM3A-to-partner and partner-to-FAM3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM3A versus ZNF445 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3A→partner) and Y-score (partner→FAM3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF445 →	-0.464	-0.433	.001	.007	3	2
COAD	MAX →	-0.488	-0.365	.002	.004	3	2
BRCA	ATM →	-0.427	-0.451	<.001	.002	3	2
COAD	CD38 →	-0.842	-0.309	.002	.002	3	2
LUAD	RXYLT1 →	-0.497	-0.419	<.001	.002	3	2
LUAD	MDM2 →	-0.724	-0.306	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,624 associations by consensus.

FAM3A vs ZNF445 — BRCA

Explore this scatter interactively →