FAM3A

Across TCGA patient cohorts, FAM3A protein abundance is significantly associated with the protein abundance of many other proteins, with 11,324 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM3A-associated proteins across cancer lineages are SP1, ZNF143, and RNH1. Each is linked with FAM3A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM3A-to-partner and partner-to-FAM3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM3A versus SP1 in UCEC, with a Pearson correlation of -0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3A→partner) and Y-score (partner→FAM3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SP1 →	-0.346	-0.474	<.001	<.001	3	4
CCRCC	ZNF143 →	-0.611	-0.472	<.001	<.001	3	4
CCRCC	RNH1 →	-0.230	-0.256	<.001	<.001	3	3
UCEC	SLC1A5 →	+0.767	+0.289	<.001	<.001	3	3
BRCA	UNK →	-0.365	-0.476	<.001	.001	3	3
BRCA	VAMP7 →	+0.532	+0.486	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,324 associations by consensus.

FAM3A vs SP1 — UCEC

Explore this scatter interactively →