FAM32A

Across TCGA cell cohorts, FAM32A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,534 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FAM32A-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Regulation of glycolytic process through fructose-6-phosphate, and Negative regulation of glycolytic process through fructose-6-phosphate. Each is linked with FAM32A in more than 14 cancer types. Because this analysis shows association rather than direction, both FAM32A-to-partner and partner-to-FAM32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by FAM32A-low versus FAM32A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM32A→partner) and Y-score (partner→FAM32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of protein localization to chromatin →	+0.128	+0.757	.005	.001	3	15
LIVER	Regulation of glycolytic process through fructose-6-phosphate →	+0.182	+0.788	<.001	<.001	3	14
LIVER	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.182	+0.788	<.001	<.001	3	14
STOMACH	Regulation of protein localization to chromatin →	+0.100	+0.672	.006	.001	2	10
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.077	+0.798	.001	<.001	3	9
SKIN	Negative regulation of calcium ion export across plasma membrane →	+0.048	+0.515	.004	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,534 associations by consensus.

Negative regulation of protein localization to chromatin by FAM32A expression — LUNG_NSCLC_LUSC

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