FAM27E5

Across TCGA patient cohorts, FAM27E5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,291 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM27E5-associated GO terms across cancer lineages are Mitochondrial gene expression, Telomerase RNA localization, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with FAM27E5 in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM27E5-to-partner and partner-to-FAM27E5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by FAM27E5-low versus FAM27E5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM27E5→partner) and Y-score (partner→FAM27E5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.108	+0.109	<.001	<.001	3	9
STAD	Telomerase RNA localization →	+0.097	+0.083	<.001	<.001	3	8
STAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.106	+0.088	<.001	<.001	3	8
STAD	Positive regulation of mitotic cell cycle →	+0.089	+0.099	<.001	<.001	3	8
STAD	Base-excision repair →	+0.091	+0.088	<.001	<.001	3	8
STAD	Protein localization to chromatin →	+0.080	+0.188	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,291 associations by consensus.

Mitochondrial gene expression by FAM27E5 expression — STAD

Explore this box plot interactively →