Across TCGA patient cohorts, FAM25A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,220 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM25A-associated proteins across cancer lineages are ECM1, PPL, and S100A16. Each is linked with FAM25A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM25A-to-partner and partner-to-FAM25A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25A→partner) and Y-score (partner→FAM25A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ECM1 →	+0.497	+0.402	<.001	.003	3	4
HNSC	PPL →	+0.577	+1.192	<.001	<.001	3	3
HNSC	S100A16 →	+0.627	+1.988	<.001	<.001	3	3
PDAC	SCEL →	+0.833	+0.549	<.001	<.001	3	3
HNSC	SCEL_S312 →	+1.169	+1.365	<.001	<.001	3	3
PDAC	SCEL_S68 →	+0.994	+0.514	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,220 associations by consensus.

Exploration

FAM25A survival (RNA) · tumor vs normal (RNA) · all FAM25A data types