Across TCGA pan-cancer cohorts, FAM24B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM24B data layer compared with 23 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM24B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM24B expression acts as an unfavorable survival marker.

SKCM are the cancer types where FAM24B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.346	0.784	.009	15	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM24B tumor-vs-normal RNA expression · all FAM24B data types