FAM243B

Across TCGA pan-cancer cohorts, FAM243B RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated FAM243B data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FAM243B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM243B expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

MESO, SKCM, and LUAD are the cancer types where FAM243B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.098	0.579	.001	108	view →
SKCM	OS	Tertile	All	0.162	0.781	<.001	45	view →
LUAD	OS	Tertile	II,III,IV	0.017	0.678	<.001	36	view →
PCPG	DFS	Tertile	All	0.084	0.774	<.001	27	view →
KIRC	OS	Tertile	II,III,IV	0.168	0.717	.022	18	view →
KIRP	DFS	Tertile	All	0.123	0.605	.009	18	view →
STAD	OS	Tertile	III,IV	1.000	0.428	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FAM243B–MESO (OS)

Open the MESO breakdown →