FAM242F

Across TCGA pan-cancer cohorts, FAM242F RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FAM242F’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM242F RNA is repressed in tumor relative to normal tissue. In most cancer types FAM242F is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and COAD are the cancer types where FAM242F tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM242F RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.160	<.001	10	view →
KIRP	All	II,III,IV	−0.198	<.001	9	view →
COAD	All	All	−0.034	.002	5	view →
UCEC	All	All	−0.059	.033	4	view →
BRCA	All	III,IV	−0.035	.048	2	view →
LUAD	All	All	+0.085	.009	1	view →
CHOL	All	All	+0.046	.042	1	view →
LUSC	All	II,III,IV	+0.022	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FAM242F–KIRC

Open the KIRC breakdown →