FAM242E

Across TCGA pan-cancer cohorts, FAM242E RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated FAM242E data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM242E RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM242E expression acts as an unfavorable survival marker.

UCEC, LUSC, and LIHC are the cancer types where FAM242E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.349	0.680	<.001	90	view →
LUSC	OS	Tertile	All	0.232	0.680	<.001	72	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	72	view →
LUAD	OS	Tertile	All	0.440	0.794	<.001	57	view →
BLCA	DFS	Tertile	IV	0.094	0.466	.013	45	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
COAD	OS	Tertile	All	0.261	0.803	.001	36	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	36	view →
SKCM	DFS	Tertile	All	0.076	0.208	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

FAM242E–UCEC (OS)

Open the UCEC breakdown →