Across TCGA pan-cancer cohorts, FAM241B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM241B data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM241B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM241B expression acts as an unfavorable survival marker.
LUAD and ACC are the cancer types where FAM241B Mutation most reproducibly stratifies survival.