FAM241B

Across TCGA patient cohorts, FAM241B mutation is significantly associated with the RNA expression of many other genes, with 487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM241B-associated genes across cancer lineages are RNU6-492P, RNU1-64P, and RNU4-26P. Each is linked with FAM241B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM241B-to-partner and partner-to-FAM241B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-492P grouped by FAM241B-low versus FAM241B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM241B→partner) and Y-score (partner→FAM241B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU1-64P →	+0.823	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
UCEC	COX5A →	+0.580	+3.332	.001	.005	3	1
UCEC	GPR157 →	+1.377	+3.201	<.001	.009	3	1
UCEC	AQP7P2 →	+0.176	+2.817	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 487 associations by consensus.

RNU6-492P by FAM241B expression — HNSC

Explore this box plot interactively →