FAM241B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM241B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM241B-associated genes across cancer lineages are pDC and Class-switched memory B-cells. Each is linked with FAM241B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM241B-to-partner and partner-to-FAM241B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by FAM241B-low versus FAM241B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM241B→partner) and Y-score (partner→FAM241B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.071+2.839.005.03431
UCECClass-switched memory B-cells →-0.059-3.321.049.01021
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

pDC by FAM241B expression — UCEC

Box plot of pDC in FAM241B-low vs FAM241B-high samples in UCEC.

Explore this box plot interactively →

Exploration