FAM241A

Across TCGA patient cohorts, FAM241A mutation is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM241A-associated genes across cancer lineages are CTDSPL2P1, CENPU, and RACGAP1. Each is linked with FAM241A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM241A-to-partner and partner-to-FAM241A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTDSPL2P1 grouped by FAM241A-low versus FAM241A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM241A→partner) and Y-score (partner→FAM241A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CTDSPL2P1 →	+0.058	+5.680	<.001	.003	3	1
UCEC	CENPU →	+0.806	+3.354	.009	.005	3	1
UCEC	RACGAP1 →	+0.866	+3.332	.006	.005	3	1
UCEC	C4orf36 →	+0.524	+3.223	<.001	.009	3	1
UCEC	ABHD18 →	+0.482	+3.332	.006	.005	3	1
UCEC	DCBLD1 →	+0.644	+3.343	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

CTDSPL2P1 by FAM241A expression — SKCM

Explore this box plot interactively →