Across TCGA patient cohorts, FAM240C protein abundance is significantly associated with the RNA expression of many other genes, with 1,498 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM240C-associated genes across cancer lineages are KRT18P34, BIK, and SLC8A3. Each is linked with FAM240C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM240C-to-partner and partner-to-FAM240C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM240C→partner) and Y-score (partner→FAM240C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT18P34 →	-1.080	-3.569	.007	.003	3	2
HNSC	BIK →	-1.091	-0.858	<.001	.004	3	1
HNSC	SLC8A3 →	+0.728	+1.492	<.001	<.001	3	1
HNSC	TCL1A →	+0.982	+0.996	<.001	.005	3	1
HNSC	DOK5 →	+0.715	+1.383	<.001	<.001	3	1
HNSC	BMP7 →	-1.508	-1.311	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,498 associations by consensus.

Exploration

FAM240C survival (RNA) · tumor vs normal (RNA) · all FAM240C data types