FAM240B

Across TCGA patient cohorts, FAM240B protein abundance is significantly associated with the go_rna of many other GO terms, with 257 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM240B-associated GO terms across cancer lineages are Response to manganese ion, Response to ionizing radiation, and Positive regulation of cytoplasmic mRNA processing body assembly. Each is linked with FAM240B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM240B-to-partner and partner-to-FAM240B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to manganese ion grouped by FAM240B-low versus FAM240B-high in HNSC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM240B→partner) and Y-score (partner→FAM240B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Response to manganese ion →	+0.110	+2.178	.002	.001	3	1
HNSC	Response to ionizing radiation →	+0.127	+1.950	.002	.006	3	1
HNSC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.162	+2.156	<.001	.001	3	1
HNSC	Regulation of epithelial to mesenchymal transition →	+0.101	+2.750	.007	.005	3	1
HNSC	Positive regulation of epithelial to mesenchymal transition →	+0.105	+2.401	<.001	<.001	3	1
HNSC	Regulation of plasminogen activation →	+0.194	+2.433	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

Response to manganese ion by FAM240B expression — HNSC

Explore this box plot interactively →