Across TCGA pan-cancer cohorts, FAM239C RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated FAM239C data layer.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher FAM239C RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM239C expression acts as an unfavorable survival marker, although some lineages such as OV and BLCA show a favorable association.
OV, BLCA, and ESCA are the cancer types where FAM239C RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.