FAM238A

Across TCGA pan-cancer cohorts, FAM238A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM238A data layer compared with 22 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher FAM238A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM238A expression acts as an unfavorable survival marker.

ESCA and SKCM are the cancer types where FAM238A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	II,III,IV	0.089	0.522	.001	12	view →
SKCM	OS	Median	II,III,IV	0.233	0.735	.015	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FAM238A–ESCA (DFS)

Open the ESCA breakdown →