FAM236C

Across TCGA patient cohorts, FAM236C RNA expression is significantly associated with the protein abundance of many other proteins, with 4,625 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM236C-associated proteins across cancer lineages are CIZ1_S514, TRIM68, and VEZF1. Each is linked with FAM236C in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM236C-to-partner and partner-to-FAM236C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM236C versus CIZ1_S514 in GBM, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM236C→partner) and Y-score (partner→FAM236C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CIZ1_S514 →	-0.734	-0.470	.001	.004	3	3
LUAD	TRIM68 →	+0.392	+0.300	<.001	.003	3	2
GBM	VEZF1 →	+0.354	+0.387	.002	<.001	3	2
GBM	VPS13D →	+0.233	+0.541	<.001	<.001	3	2
GBM	WIPI1 →	-0.302	-0.398	.003	<.001	3	2
GBM	WWP2 →	+0.250	+0.442	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,625 associations by consensus.

FAM236C vs CIZ1_S514 — GBM

Explore this scatter interactively →