FAM236B

Across TCGA pan-cancer cohorts, FAM236B RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated FAM236B data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher FAM236B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM236B expression acts as an unfavorable survival marker.

LGG and LAML are the cancer types where FAM236B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.080	0.833	<.001	36	view →
LAML	DFS	Tertile	All	0.082	0.582	.004	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FAM236B–LGG (DFS)

Open the LGG breakdown →