FAM234B

Across TCGA cell cohorts, FAM234B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,642 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM234B-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Negative regulation of gene expression, epigenetic, and Heterochromatin organization. Each is linked with FAM234B in more than 12 cancer types. Because this analysis shows association rather than direction, both FAM234B-to-partner and partner-to-FAM234B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by FAM234B-low versus FAM234B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM234B→partner) and Y-score (partner→FAM234B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.077	+0.723	<.001	<.001	3	13
BONE	Negative regulation of gene expression, epigenetic →	+0.080	+0.644	<.001	.001	3	13
BONE	Heterochromatin organization →	+0.085	+0.772	<.001	<.001	3	13
BONE	Heterochromatin formation →	+0.080	+0.573	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule nucleation →	+0.131	+1.007	<.001	.002	3	10
BONE	tRNA transcription →	+0.130	+0.520	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,642 associations by consensus.

Epigenetic regulation of gene expression by FAM234B expression — BONE

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