FAM230J

Across TCGA patient cohorts, FAM230J mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM230J-associated genes across cancer lineages are RNU6-369P, RNA5SP472, and RNU6-715P. Each is linked with FAM230J in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM230J-to-partner and partner-to-FAM230J results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-369P grouped by FAM230J-low versus FAM230J-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230J→partner) and Y-score (partner→FAM230J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-369P →	+0.302	+8.471	<.001	.005	3	1
BRCA	RNA5SP472 →	+0.332	+7.731	<.001	.009	3	1
BRCA	RNU6-715P →	+0.618	+9.057	<.001	.003	3	1
BRCA	RNU11-5P →	+0.246	+7.731	<.001	.009	3	1
BRCA	MTND1P1 →	+0.124	+7.731	<.001	.009	3	1
ESCA	RNA5SP293 →	+0.466	+5.247	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RNU6-369P by FAM230J expression — BRCA

Explore this box plot interactively →