FAM230I

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM230I RNA expression is significantly associated with the go_rna of many other GO terms, with 7,013 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM230I-associated GO terms across cancer lineages are DNA modification, Regulation of intracellular steroid hormone receptor signaling pathway, and Negative regulation of gene expression, epigenetic. Each is linked with FAM230I in more than 20 cancer types. Because this analysis shows association rather than direction, both FAM230I-to-partner and partner-to-FAM230I results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA modification grouped by FAM230I-low versus FAM230I-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230I→partner) and Y-score (partner→FAM230I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADDNA modification →+0.049+0.212<.001<.001321
STADRegulation of intracellular steroid hormone receptor signaling pathway →+0.080+0.290<.001<.001321
ESCANegative regulation of gene expression, epigenetic →+0.077+0.373<.001<.001321
STADPeptidyl-lysine modification →+0.057+0.192<.001<.001321
ESCANucleotide-excision repair →+0.062+0.357<.001<.001221
STADAnterior/posterior pattern specification →+0.040+0.165<.001<.001320
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,013 associations by consensus.

DNA modification by FAM230I expression — STAD

Box plot of DNA modification in FAM230I-low vs FAM230I-high samples in STAD.

Explore this box plot interactively →

Exploration