FAM230I

Across TCGA patient cohorts, FAM230I mutation is significantly associated with the RNA expression of many other genes, with 253 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM230I-associated genes across cancer lineages are RN7SL126P, HNRNPCL3, and AQP7P3. Each is linked with FAM230I in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM230I-to-partner and partner-to-FAM230I results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL126P grouped by FAM230I-low versus FAM230I-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230I→partner) and Y-score (partner→FAM230I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL126P →	+0.218	+2.496	.003	.004	3	1
UCEC	HNRNPCL3 →	+0.082	+3.193	<.001	<.001	3	1
UCEC	AQP7P3 →	+0.053	+3.997	<.001	.001	3	1
UCEC	RN7SL134P →	+0.138	+2.599	.002	.009	3	1
UCEC	MIR4744 →	+0.384	+2.377	.007	.008	3	1
UCEC	MIR548AI →	+0.235	+4.414	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

RN7SL126P by FAM230I expression — UCEC

Explore this box plot interactively →