FAM230F

Across TCGA pan-cancer cohorts, FAM230F RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated FAM230F data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher FAM230F RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM230F expression acts as an unfavorable survival marker.

ESCA, UCEC, and SARC are the cancer types where FAM230F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.103	0.868	<.001	36	view →
UCEC	OS	Tertile	III,IV	0.054	0.588	.007	36	view →
SARC	OS	Tertile	All	0.252	0.771	<.001	27	view →
LUSC	OS	Tertile	III,IV	0.047	0.664	<.001	27	view →
SKCM	DFS	Tertile	All	0.179	0.730	<.001	24	view →
LGG	OS	Tertile	All	0.683	0.900	<.001	24	view →
KIRC	DFS	Tertile	All	0.150	0.631	<.001	18	view →
GBM	OS	Tertile	All	0.120	0.420	.028	9	view →
ACC	DFS	Tertile	All	0.195	0.748	.003	9	view →
COAD	OS	Tertile	III,IV	0.208	0.791	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

FAM230F–ESCA (OS)

Open the ESCA breakdown →