FAM230C

Across TCGA patient cohorts, FAM230C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,983 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM230C-associated GO terms across cancer lineages are Regulation of cytokinesis, Positive regulation of mitotic cell cycle, and Positive regulation of cell cycle phase transition. Each is linked with FAM230C in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM230C-to-partner and partner-to-FAM230C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytokinesis grouped by FAM230C-low versus FAM230C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM230C→partner) and Y-score (partner→FAM230C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cytokinesis →	+0.059	+0.412	<.001	<.001	3	16
STAD	Positive regulation of mitotic cell cycle →	+0.057	+0.321	<.001	<.001	3	16
STAD	Positive regulation of cell cycle phase transition →	+0.056	+0.319	<.001	<.001	3	15
STAD	Positive regulation of mitotic cell cycle phase transition →	+0.056	+0.345	<.001	<.001	3	15
STAD	Mitotic metaphase chromosome alignment →	+0.069	+0.322	<.001	<.001	3	15
STAD	Regulation of chromosome organization →	+0.063	+0.318	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,983 associations by consensus.

Regulation of cytokinesis by FAM230C expression — STAD

Explore this box plot interactively →