Across TCGA pan-cancer cohorts, FAM229B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FAM229B data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM229B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM229B expression acts as an unfavorable survival marker.

LUAD are the cancer types where FAM229B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.090	0.812	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM229B tumor-vs-normal RNA expression · all FAM229B data types