Across TCGA patient cohorts, FAM228A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,345 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM228A-associated proteins across cancer lineages are FHL3, BGN, and CAVIN3. Each is linked with FAM228A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM228A-to-partner and partner-to-FAM228A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM228A→partner) and Y-score (partner→FAM228A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FHL3 →	+0.573	+0.182	.006	.007	2	5
CCRCC	BGN →	+0.838	+0.394	<.001	<.001	3	4
CCRCC	CAVIN3 →	+0.508	+0.280	<.001	.001	3	4
LSCC	FERMT2 →	+0.538	+0.325	<.001	<.001	3	4
OV	FLNA_S2152 →	+0.883	+0.224	<.001	.006	3	4
OV	OLFML3 →	+0.788	+0.175	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,345 associations by consensus.

Exploration

FAM228A survival (RNA) · tumor vs normal (RNA) · all FAM228A data types