Across TCGA patient cohorts, FAM228A mutation is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM228A-associated genes across cancer lineages are CICP18, BPNT2P, and MIR7976. Each is linked with FAM228A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM228A-to-partner and partner-to-FAM228A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM228A→partner) and Y-score (partner→FAM228A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CICP18 →	+0.025	+4.426	<.001	.006	3	2
READ	BPNT2P →	+0.148	+6.681	<.001	<.001	3	2
UCEC	MIR7976 →	+0.445	+2.868	.002	.006	3	1
UCEC	RPS29P32 →	+0.642	+3.014	<.001	.004	3	1
UCEC	RN7SL478P →	+0.339	+2.939	<.001	.001	3	1
BRCA	WBP1LP3 →	+0.148	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

Exploration

FAM228A survival (RNA) · tumor vs normal (RNA) · all FAM228A data types