FAM222B

Across TCGA patient cohorts, FAM222B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM222B-associated proteins across cancer lineages are WDR5, XPO1, and SSB. Each is linked with FAM222B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM222B-to-partner and partner-to-FAM222B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM222B versus WDR5 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM222B→partner) and Y-score (partner→FAM222B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR5 →	+0.278	+0.478	<.001	<.001	3	5
LSCC	XPO1 →	+0.202	+0.478	<.001	<.001	3	5
GBM	SSB →	+0.242	+0.419	<.001	<.001	3	5
LSCC	SF3B3 →	+0.263	+0.676	<.001	<.001	3	5
LSCC	DDX23 →	+0.199	+0.369	<.001	<.001	3	5
GBM	BUB3 →	+0.291	+0.544	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,266 associations by consensus.

FAM222B vs WDR5 — GBM

Explore this scatter interactively →