FAM222B

Across TCGA patient cohorts, FAM222B protein abundance is significantly associated with the RNA expression of many other genes, with 2,416 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM222B-associated genes across cancer lineages are CDK5RAP3, DET1, and MFSD2A. Each is linked with FAM222B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM222B-to-partner and partner-to-FAM222B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM222B versus CDK5RAP3 in BRCA, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM222B→partner) and Y-score (partner→FAM222B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDK5RAP3 →	-0.547	-0.413	.002	<.001	3	2
BRCA	DET1 →	-0.503	-0.355	<.001	.004	3	2
UCEC	MFSD2A →	+1.828	+0.504	.004	.001	3	2
GBM	SCAND2P →	-0.366	-0.613	<.001	<.001	3	2
BRCA	ZNF789 →	-0.492	-0.361	.001	.005	3	2
GBM	RRS1-AS1 →	-0.397	-0.512	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,416 associations by consensus.

FAM222B vs CDK5RAP3 — BRCA

Explore this scatter interactively →