FAM221A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM221A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,096 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAM221A-associated proteins across cancer lineages are MYO6, ATP6V1C1, and YWHAZ. Each is linked with FAM221A in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM221A-to-partner and partner-to-FAM221A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM221A→partner) and Y-score (partner→FAM221A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMYO6 →+0.465+0.609<.001<.00134
OVATP6V1C1 →-0.394-0.643<.001.00134
LSCCYWHAZ →-0.332-0.644<.001<.00134
HNSCMTSS1 →-0.597-0.553<.001<.00134
HNSCARFGEF3 →+0.490+0.592<.001<.00134
LSCCPICK1 →+0.428+0.686<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,096 associations by consensus.

Exploration