Across TCGA cell cohorts, FAM221A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,309 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM221A-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Regulation of myoblast fusion, and Negative regulation of T-helper 17 cell lineage commitment. Each is linked with FAM221A in more than 9 cancer types. Because this analysis shows association rather than direction, both FAM221A-to-partner and partner-to-FAM221A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM221A→partner) and Y-score (partner→FAM221A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.087	+1.567	.001	.001	3	9
LIVER	Regulation of myoblast fusion →	+0.085	+2.009	<.001	.003	2	10
URINARY_TRACT	Negative regulation of T-helper 17 cell lineage commitment →	-0.525	-2.010	.002	<.001	3	8
OVARY	Oxidative phosphorylation →	+0.084	+1.539	.004	.002	3	7
LIVER	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+1.928	.005	.005	3	7
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.091	+1.044	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,309 associations by consensus.

Exploration

FAM221A survival (RNA) · tumor vs normal (RNA) · all FAM221A data types