Across TCGA patient cohorts, FAM220CP mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM220CP-associated genes across cancer lineages are Ku80, p62 Lck ligand, and Rab11. Each is linked with FAM220CP in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM220CP-to-partner and partner-to-FAM220CP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM220CP→partner) and Y-score (partner→FAM220CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.316	+2.183	.010	.035	3	1
UCEC	p62 Lck ligand →	+0.344	+2.179	.043	.034	3	1
UCEC	Rab11 →	-0.202	-3.150	.007	.019	3	1
UCEC	Annexin-1 →	+0.722	+2.827	.008	.035	3	1
UCEC	Tuberin →	+0.405	+2.817	.004	.036	3	1
UCEC	4E-BP1_pT37_T46 →	-0.520	-2.986	.008	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

FAM220CP survival (RNA) · tumor vs normal (RNA) · all FAM220CP data types