FAM220A

Across TCGA patient cohorts, FAM220A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM220A-associated proteins across cancer lineages are NUDCD3, PUS7, and YWHAQ. Each is linked with FAM220A in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM220A-to-partner and partner-to-FAM220A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM220A versus NUDCD3 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM220A→partner) and Y-score (partner→FAM220A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUDCD3 →	+0.365	+0.813	<.001	<.001	3	7
LSCC	PUS7 →	+0.505	+0.481	<.001	<.001	3	6
PDAC	YWHAQ →	+0.321	+0.311	.001	.001	3	6
LSCC	NUDT1 →	+0.529	+0.645	<.001	<.001	3	6
CCRCC	DOCK8_S904 →	-0.545	-0.450	<.001	<.001	3	6
LSCC	FOXK1 →	+0.394	+0.537	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,261 associations by consensus.

FAM220A vs NUDCD3 — HNSC

Explore this scatter interactively →