FAM220A

Across TCGA cell cohorts, FAM220A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,787 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FAM220A-associated GO terms across cancer lineages are Meiotic mismatch repair, Protein polyubiquitination, and Positive regulation of isotype switching to IgG isotypes. Each is linked with FAM220A in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM220A-to-partner and partner-to-FAM220A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by FAM220A-low versus FAM220A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM220A→partner) and Y-score (partner→FAM220A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Meiotic mismatch repair →	+0.123	+1.058	<.001	<.001	3	16
OVARY	Protein polyubiquitination →	+0.043	+0.520	<.001	.001	3	13
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.162	+0.967	<.001	<.001	3	12
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.125	+0.977	.002	<.001	3	10
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.088	+0.727	.002	<.001	3	10
SOFT_TISSUE	Positive regulation of translational initiation →	+0.099	+0.574	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,787 associations by consensus.

Meiotic mismatch repair by FAM220A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →