FAM219B

Across TCGA patient cohorts, FAM219B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,029 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FAM219B-associated proteins across cancer lineages are HDGFL3, HSP90B1, and HSPA5. Each is linked with FAM219B in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM219B-to-partner and partner-to-FAM219B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM219B versus HDGFL3 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM219B→partner) and Y-score (partner→FAM219B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HDGFL3 →	+0.665	+0.671	<.001	<.001	3	6
LUAD	HSP90B1 →	-0.321	-0.351	.007	.002	3	6
GBM	HSPA5 →	-0.275	-0.207	.001	.009	3	6
BRCA	SND1 →	-0.275	-0.356	<.001	<.001	3	6
LSCC	IGF1R →	+0.572	+0.445	<.001	<.001	3	5
GBM	TTC33 →	+0.423	+0.355	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,029 associations by consensus.

FAM219B vs HDGFL3 — OV

Explore this scatter interactively →