FAM219A

Across TCGA pan-cancer cohorts, FAM219A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM219A data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher FAM219A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM219A expression acts as an unfavorable survival marker.

STAD and LUAD are the cancer types where FAM219A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.183	0.677	.004	24	view →
LUAD	OS	Median	All	0.276	0.697	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FAM219A–STAD (OS)

Open the STAD breakdown →