FAM219A

Across TCGA patient cohorts, FAM219A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,846 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM219A-associated proteins across cancer lineages are FAM219A_S72, HTRA1, and PLOD3. Each is linked with FAM219A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM219A-to-partner and partner-to-FAM219A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM219A versus FAM219A_S72 in LUAD, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM219A→partner) and Y-score (partner→FAM219A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM219A_S72 →	+0.606	+0.497	<.001	<.001	3	6
OV	HTRA1 →	+0.878	+0.924	<.001	<.001	3	4
PDAC	PLOD3 →	+0.394	+0.467	<.001	<.001	3	4
LSCC	DNAJA1 →	+0.255	+0.493	<.001	<.001	3	4
PDAC	FAM219A_S115 →	+0.658	+0.772	<.001	.003	3	4
UCEC	KIF13B →	-0.517	-0.655	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,846 associations by consensus.

FAM219A vs FAM219A_S72 — LUAD

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