FAM219A

Across TCGA patient cohorts, FAM219A protein abundance is significantly associated with the RNA expression of many other genes, with 4,205 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM219A-associated genes across cancer lineages are AGBL2, CLTA, and MT1E. Each is linked with FAM219A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM219A-to-partner and partner-to-FAM219A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM219A versus AGBL2 in CCRCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM219A→partner) and Y-score (partner→FAM219A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	AGBL2 →	-0.455	-0.551	.007	.007	3	3
LSCC	CLTA →	+0.851	+0.411	<.001	<.001	3	3
PDAC	MT1E →	+1.243	+0.479	.008	.004	3	2
GBM	FUT9 →	+1.221	+0.272	.005	.001	3	2
GBM	HS6ST3 →	+1.182	+0.254	<.001	.002	3	2
GBM	SEPTIN3 →	+0.847	+0.205	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,205 associations by consensus.

FAM219A vs AGBL2 — CCRCC

Explore this scatter interactively →