FAM219A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM219A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM219A-associated genes across cancer lineages are CD4+ Tem and Neurons. Each is linked with FAM219A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM219A-to-partner and partner-to-FAM219A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by FAM219A-low versus FAM219A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM219A→partner) and Y-score (partner→FAM219A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACD4+ Tem →+0.043+6.234<.001.02632
UCECNeurons →-0.021-2.978.047.03721
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tem by FAM219A expression — BRCA

Box plot of CD4+ Tem in FAM219A-low vs FAM219A-high samples in BRCA.

Explore this box plot interactively →

Exploration